0.832
Pearson Correlation
vs. Akita benchmark
10×
Training Speedup
vs. quadratic baseline
30×
Attribution Speedup
gradient interpretability
Helical twist, slide, bendability -> these are the forces that fold your genome into 3D structure. Every model that treats DNA as a sequence of letters is missing the physics. GoldBEAM is built on what DNA actually is.
Explore the technology0.832
Pearson Correlation
vs. Akita benchmark
10×
Training Speedup
vs. quadratic baseline
30×
Attribution Speedup
gradient interpretability
Product
SWAEV Genomics is building a cloud-based API that lets researchers and biotech companies analyze complex genomic segments with models that physically map out why they make structural decisions. Rather than relying on rigid statistical memorization, our infrastructure strips away the black box to reveal underlying regulatory and structural paradigms natively aligned with physical DNA rules.
SWAEV operates as a specialized expert within larger Mixture of Experts (MoE) networks, functioning as an intrinsic interpretability layer that grounds foundational biological models by exposing the underlying sequence motifs and biophysical properties governing predictions.
Key use cases:
We are currently seeking early access partners to validate our platform on proprietary structural datasets.
Technology
Our platform extends the open-source SPECTRE‑Wave architecture with structural mapping layers explicitly engineered for genomic sequences. Standard Transformer setups rely on expensive algorithms that scale quadratically with length, severely bounding their window size. By mapping interactions using continuous wave propagation dynamics, we replace raw attention mechanics entirely to achieve an ultra-scalable architecture.
Our infrastructure natively handles massive 1-Megabase sequence windows while tracking physical constraints across distinct, scale-specific receptive fields simultaneously. This grants an immediate performance boost of over 10x during training and 30x during reverse-engineering gradient attribution compared to classic quadratic setups of equal length.
We have successfully validated these mechanics across E. coli, yeast, and human validation windows. In benchmark tests, the model's inner filter weights autonomously converged on 11 fundamental biophysical properties of DNA -> including Helical Twist, Slide, and Bendability -> without any manual target hardcoding.
Research Infrastructure
These results were produced on a repurposed HP ProLiant DL380p Gen8 with an RTX 3060 12GB mounted directly to the chassis. Benchmark-competitive accuracy, built from a salvaged rack. That's our architecture doing the lifting, not the hardware.
To expand our current local prototyping setup into massive, multi-genome scale pipelines, we are actively setting up compute partnerships leveraging dedicated A100/H100 clusters or Google Cloud TPUs.
GoldBEAM
GoldBEAM takes a raw DNA sequence -> up to 1 Megabase -> and predicts the full 3D chromatin contact map. TAD blocks, enhancer-promoter loops, and insulator boundaries emerge directly from sequence information alone, no Hi-C data required at inference time.
The contact map is the output. Each pixel represents the predicted contact probability between two genomic loci. Bright regions are high-contact zones -> the TAD blocks your genome actually inhabits. The diagonal is the backbone of local proximity; the square clusters are the domains where gene regulation happens.
Because the model is built on physical wave propagation rather than attention, it natively captures multi-scale structure -> from 4 kbp loops all the way to macro-compartment boundaries -> in a single forward pass.
Simulated GoldBEAM output · BRCA1 locus · Homo sapiens
Research Suite
The GoldBEAM TUI ships with seven built-in experiments -> not just predictions. Run CTCF motif deletion sweeps, map TAD boundary attribution, design synthetic insulators, and overlay empirical Hi-C data against model output. Every result is logged to structured reports.
Built for researchers who live in the terminal. No GUI, no notebook, no friction.
Status
Company
SWAEV Genomics is an Irish registered company building interpretable AI for genomic analysis. We combine signal processing with deep learning to make biological predictions transparent and trustworthy. "SWAEV" derives from "Sequence" + "Wave" -> our core technology.
Supported by
Accepted into the Google for Startups Cloud Program
Contact
For early access requests, architecture validation reports, or computational pipeline collaborations.
SWAEV B2B Platform
To integrate subquadratic structural chromatin maps into your research pipelines or command-line analysis scripts, authenticate below to generate secure TUI execution keys.
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Lab Simulation 04-B
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Your current active tier is Individual Sandbox ($0/mo). Expand to manage or upgrade.
Sandbox Tier
Independent DevsPerfect for local development, trial runs, and light genomic processing simulations.
Popular Tier
PhD CandidatesEnhanced limits for academic labs and professional genetic researchers.
Department Tier
Lab Core / PIsRobust computing capacity with dedicated resources for academic departments and core facilities.
Sovereign Tier
Pharma / BiotechSovereign infrastructure custom-tuned for enterprise commercial pharma and biotech R&D pipelines.
Subscribed Metrics
Terminal Credentials
Paste this key into the Bacteriophage terminal TUI config prompt. Treat it with absolute confidentiality.
Active Compute Slots
These tasks are currently allocated to your high-throughput GPU worker node slots. If a task is taking longer than expected or you wish to reclaim a slot immediately, you can securely abort it below.
Visual Genomic Analytics
Hover over the heatmap below to scan topologically associating domains (TADs) and predict distal enhancer-promoter loops in real-time. This live visual represents subquadratic chromatin contact mapping.
Scroll to zoom · drag to pan · dbl-click to reset
Live Inference
Paste a genomic region in FASTA or raw sequence format (800 kbp–1.2 Mbp). GoldBEAM tokenizes and submits the job using your API key -> the result renders directly on the contact map above when complete.